HOW TO ONTAIN TWO OPTICAL ANTIPODES OF AN OCTAHYDRO-2H-PYRIDO PYRAZINE STARTING FROM A SINGLE CHIRAL SYNTHON

Article abstract of DOI:10.1016/S0957-4166(00)80040-3

The synthesis of a (+)-(R,S)-2-aryl-4-methyl-3-oxo, octahydro-2H-pyrido<1,2-a>pyrazine and of its optical antipode (-)-(S,R)-2-aryl-4-methyl-3-oxo, octahydro-2H-pyrido<1,2-a>pyrazine, with a single synthetic sequence, and by making use of the natural ethy