Journal of the Chemical Society. Perkin transactions I p. 1139 - 1142 (1991)
Update date:2022-08-03
Topics:
Berenyi, Sandor
Gulyas, Gyoengyi
Batta, Gyula
Gunda, Tamas
Makleit, Sandor
Azidolysis of C-19 diastereoisomer tosylesters of morphine derivatives possessing a bridged ring C has been studied and 4-azatetracyclo<4.4.02,4.03,8>decanes 6b, 6d, and 6f were formed via the substitution and subsequent intramolecular cyclization of the (R)-C-19 tosylesters 4b, 4d, and 4f, and primarily the ethylidene derivatives 7a, 7b and 7c were obtained from (S)-C-19 tosylesters 4c, 4e and 4g.According to our experience the course of the reaction depends on the configuration of the C-19 centre of chirality and on the spatial requirement of the substituent on C-6.
View MoreGuilin Zhenda Bio-Tech Co., Ltd.
Contact:86-773-3568977
Address:-Yangtang shangshui industry park, Lingui county,
Jiangsu Hualun Chemical Industry Co., Ltd
website:http://www.hualunchem.com
Contact:+86-0514-86464168 86507985
Address:39# Middle Renmin Road, Dinghuo Town
Contact:--
Address:80G, No.1 Building, Guodu Development Mansion, No. 182 Zhaohui Road, Hangzhou City, Zhejiang Province,China.
Goldwills Pharmaceuticals Co., Ltd.
Contact:0916-2237889 13991621155
Address:North Suburb of Hanzhong city, Shaanxi Province
puyang hongda shengdao new material co.,ltd.
Contact:+86-393- 4896278
Address:No.29 East Zhongyuan Road
Doi:10.1039/c1ce05794d
(2011)Doi:10.1016/j.tetlet.2008.01.018
(2008)Doi:10.1016/j.poly.2013.02.051
(2013)Doi:10.1039/c0mb00227e
(2011)Doi:10.1021/jo00020a017
(1991)Doi:10.1016/j.tet.2011.12.018
(2012)
