Journal of the Chemical Society. Perkin transactions I p. 1139 - 1142 (1991)
Update date:2022-08-03
Topics:
Berenyi, Sandor
Gulyas, Gyoengyi
Batta, Gyula
Gunda, Tamas
Makleit, Sandor
Azidolysis of C-19 diastereoisomer tosylesters of morphine derivatives possessing a bridged ring C has been studied and 4-azatetracyclo<4.4.02,4.03,8>decanes 6b, 6d, and 6f were formed via the substitution and subsequent intramolecular cyclization of the (R)-C-19 tosylesters 4b, 4d, and 4f, and primarily the ethylidene derivatives 7a, 7b and 7c were obtained from (S)-C-19 tosylesters 4c, 4e and 4g.According to our experience the course of the reaction depends on the configuration of the C-19 centre of chirality and on the spatial requirement of the substituent on C-6.
View MoreJiangxi Hito Chemical Co., Ltd.
Contact:+86-792-3170318
Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Nanjing Raise Pharmatech Co., Ltd
website:http://www.raisechem.com
Contact:+86-25-58649566
Address:B381,No.606,Ningliu Road,Jiangbei New Area,Nanjing,Jiangsu Province,China
Shuanghe Bio-Technology Limited(expird)
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Hebei Think-Do Environment Co., Ltd
website:http://www.thinkdo-environment.com
Contact:0311-86510809-
Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Lonzeal Pharmaceuticals Co., Ltd.
website:http://www.lonzeal.com
Contact:+86-13381011962
Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Doi:10.1039/c1ce05794d
(2011)Doi:10.1016/j.tetlet.2008.01.018
(2008)Doi:10.1016/j.poly.2013.02.051
(2013)Doi:10.1039/c0mb00227e
(2011)Doi:10.1021/jo00020a017
(1991)Doi:10.1016/j.tet.2011.12.018
(2012)
