Structure-activity relationship of naphthaldehydethiosemicarbazones in melanogenesis inhibition

DOI: 10.1016/j.bmcl.2011.12.035

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 886 - 889 (2012)

Update date:2022-08-04

Topics:

Authors:

Thanigaimalai, Pillaiyar

Rao, Eeda Venkateswara

Lee, Ki-Cheul

Sharma, Vinay K.

Roh, Eunmiri

Kim, Youngsoo

Jung, Sang-Hun

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bmcl.2011.12.035

2-(Naphthalen-1-ylmethylene)hydrazinecarbothioamide (14, IC₅₀ = 1.1 μM) was discovered as a highly potent inhibitor of melanogenesis. To define the role of hydrogens (at N1 and N3) and sulfur in 14, a series of analogs 15a-p were synthesized an

Full text of DOI:10.1016/j.bmcl.2011.12.035

Products guided by the article

Product name:

Cas No:1357363-40-6

R&D Labs maybe for 1357363-40-6

Lian Xing Chemical Co.,Ltd.

Contact:0792-8228321

Address:10TH Floor No.121 binjiang Road Xunyang District
Changzhou Anyi Biochem Co., Ltd.(expird)

Contact:+86-519-88836158

Address:no,51 caoda
QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Exploiter Molybdenum Co.,Ltd

Contact:86-379-63338609

Address:Jiudian Village,Deting Town,Song County,Luoyang
TLS PHARMACEUTICAL CO.,LTD

Contact:0833-5590788/5590338/5590055

Address:Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark

Relevant to this article

Molecular and macromolecular engineering with viologens as building blocks: Rational design of phosphorus-viologen dendritic structures

Doi:10.1002/ejoc.201101376
(2012)
Synthesis and Reaction of Organoplatinum Compounds of C60, C60Pt_n

Doi:10.1246/cl.1994.1207
(1994)
A novel application of a [3+2] cycloaddition reaction for the synthesis of the piperazinone rings of pseudotheonamides A₁ and A₂

Doi:10.1016/S0040-4039(02)00133-8
(2002)
Synthesis and Molecular Structure of Novel Zinc(II) Complexes: <n>, and

Doi:10.1039/DT9910001569
(1991)
HOMOLOGATION OF ACIDS via CARBON RADICALS GENERATED FROM THE ACYL DERIVATIVES OF N-HYDROXY-2-THIOPYRIDONE. (THE TWO-CARBON PROBLEM).

Doi:10.1016/S0040-4039(00)92693-5
(1991)
Evaluation of sulfatase-directed quinone methide traps for proteomics

Doi:10.1016/j.bmc.2011.04.044
(2012)

Article Doi