Asymmetric synthesis of β-lactams and N-benzoyl-3-phenylisoserines via the Staudinger reaction

DOI: 10.1016/S0040-4039(00)79708-5

Source and publish data:

Tetrahedron Letters p. 3151 - 3154 (1991)

Update date:2022-08-04

Topics:

Authors:

Georg Georg

Mashava Mashava

Akgun Akgun

Milstead

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Article abstract of DOI:10.1016/S0040-4039(00)79708-5

Reaction of benzaldimine derived from 2,3,4,6-tetra-O-acetyl-β-D-galactoseamine with acid chloride yields cis β-lactam as a single diastereoisomer. Hydrolysis of β-lactam followed by N-benzoylation provides access toward N-benzoyl-(2S,3R)-3-phenylisoserin

Full text of DOI:10.1016/S0040-4039(00)79708-5

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