Tetrahedron p. 4675 - 4682 (1991)
Update date:2022-07-30
Topics:
Speybroeck, R. Van
Guo, H.
Eycken, J. Van der
Vandewalle, M.
An enantioselective total synthesis of (-)-epipodophyllotoxin (2) and hence of (-)-podophyllotoxin (1) is described, involving as key steps a conjugate addition on butenolide 13 as the chiral template, a stereoselective aldol condensation on 11a and a ste
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