A Highly Regioselective Conversion of Epoxides to Halohydrins by Lithium Halides

DOI: 10.1016/0040-4039(91)80676-W

Source and publish data:

Tetrahedron Letters p. 3021 - 3024 (1991)

Update date:2022-08-03

Topics:

Authors:

Bajwa, Joginder S.

Anderson, Robert C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(91)80676-W

Lithium halides in the presence of an acid (pK_a < 13) react with epoxides regioselectively to give vicinal halohydrins in high yields.The simplicity and convenience of this procedure makes it attractive for large scale synthesis.

Full text of DOI:10.1016/0040-4039(91)80676-W

Products guided by the article

Product name:(2-Hydroxy-3-iodo-propyl)-phosphonic acid dibenzyl ester

Cas No:136258-98-5

R&D Labs maybe for 136258-98-5

Nanjing Capatue Chemical Co., Ltd

Contact:+86-25-86371192 +86-025-85720158

Address:No.20 Jiangjun Avenue, Jiangning Economic & Technical Development Zone
SHANDONG AONA CHEMICAL CO.,LTD.

Contact:86-532-85762926

Address:LIUYUAN TOWN, ZAOZHUANG CITY, SHANGDONG PROVINCE.
ClickChem Technology Co., Limited

Contact:+86-0310-6519966/0531-52893837

Address:No.750 Shunhua Road, High-Tech Zone, Jinan city, Shandong China
Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Reliable Pharma Technology (Shanghai) Co., Ltd.

Contact:0086-21-67676847-8008

Address:Lane 1500, No.68, Xinfei Road, Songjiang District, Shanghai, 201611, P.R.China.

Relevant to this article

Practical synthesis of four different pseudoenantiomeric organocatalysts with both cis- and trans-substituted 1,2-cis-cyclohexanediamine structures from a common intermediate

Doi:10.1016/j.tet.2018.05.035
(2018)
N-Activated β-lactams as versatile reagents for acyl carrier protein labeling

Doi:10.1039/c2ob06846j
(2012)
Redox potentials, laccase oxidation, and antilarval activities of substituted phenols

Doi:10.1016/j.bmc.2012.01.021
(2012)
Synthesis of 3′-azido-5′-homothymidine analogs

Doi:10.1016/S0040-4039(00)92706-0
(1991)
Unexpected Contrasteric Alkylation Leading to a Model for Five-Membered Ring Enolate Alkylation: Short Stereoselective Synthesis of (+/-)-Acetomycin

Doi:10.1021/jo00121a025
(1995)
Synthesis of (+)-2,8-dihydroxyethyl-1,4,7,10-tetraoxaspiro[5.5]undecane from (R)-4-hydroxymethyl-2,2-dimethyl-1,3-dioxane

Doi:10.1016/S0957-4166(96)00517-4
(1997)

Article Doi