A Highly Regioselective Conversion of Epoxides to Halohydrins by Lithium Halides

DOI: 10.1016/0040-4039(91)80676-W

Source and publish data:

Tetrahedron Letters p. 3021 - 3024 (1991)

Update date:2022-08-03

Topics:

Authors:

Bajwa, Joginder S.

Anderson, Robert C.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(91)80676-W

Lithium halides in the presence of an acid (pK_a < 13) react with epoxides regioselectively to give vicinal halohydrins in high yields.The simplicity and convenience of this procedure makes it attractive for large scale synthesis.

Full text of DOI:10.1016/0040-4039(91)80676-W

Products guided by the article

Product name:(2-Hydroxy-3-iodo-propyl)-phosphonic acid dibenzyl ester

Cas No:136258-98-5

R&D Labs maybe for 136258-98-5

Tianjin Ingenochem Technology Co.,Ltd

Contact:+86-22-23677060

Address:Hitech Green Industry Park K2-9-602, Nankai district
Maithili Life Sciences

Contact:+91 9963263336

Address:Plot#146A, IDA Mallapur, Hyderabad - 500072
Nanjing yieldpharma co.ltd

Contact:13813902930 025-52714267

Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone
Shanghai Goyic Pharmaceutical&Chemical Co,. Ltd

Contact:+86-021-60275964

Address:No. 528 ruiqing road

Relevant to this article

Practical synthesis of four different pseudoenantiomeric organocatalysts with both cis- and trans-substituted 1,2-cis-cyclohexanediamine structures from a common intermediate

Doi:10.1016/j.tet.2018.05.035
(2018)
N-Activated β-lactams as versatile reagents for acyl carrier protein labeling

Doi:10.1039/c2ob06846j
(2012)
Redox potentials, laccase oxidation, and antilarval activities of substituted phenols

Doi:10.1016/j.bmc.2012.01.021
(2012)
Synthesis of 3′-azido-5′-homothymidine analogs

Doi:10.1016/S0040-4039(00)92706-0
(1991)
Unexpected Contrasteric Alkylation Leading to a Model for Five-Membered Ring Enolate Alkylation: Short Stereoselective Synthesis of (+/-)-Acetomycin

Doi:10.1021/jo00121a025
(1995)
Synthesis of (+)-2,8-dihydroxyethyl-1,4,7,10-tetraoxaspiro[5.5]undecane from (R)-4-hydroxymethyl-2,2-dimethyl-1,3-dioxane

Doi:10.1016/S0957-4166(96)00517-4
(1997)

Article Doi