A Highly Regioselective Conversion of Epoxides to Halohydrins by Lithium Halides

DOI: 10.1016/0040-4039(91)80676-W

Source and publish data:

Tetrahedron Letters p. 3021 - 3024 (1991)

Update date:2022-08-03

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Authors:

Bajwa, Joginder S.

Anderson, Robert C.

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Article abstract of DOI:10.1016/0040-4039(91)80676-W

Lithium halides in the presence of an acid (pK_a < 13) react with epoxides regioselectively to give vicinal halohydrins in high yields.The simplicity and convenience of this procedure makes it attractive for large scale synthesis.

Full text of DOI:10.1016/0040-4039(91)80676-W

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