Collection of Czechoslovak Chemical Communications p. 1127 - 1133 (1992)
Update date:2022-09-26
Topics:
Palat, Karel
Celadnik, Milan
Danek, Jaroslav
Varkonda, Stefan
Substituted phenylammonium chlorides react with cyanamide to give the corresponding phenylguanidines which on treatment with chloroformate esters give N-subst.phenyl-N,N''-guanidinedicarboxylic acid esters.All substances prepared have been tested for their anthelmintic activity against the model helminths Nippostrongylus brasiliensis and Hymenolepis nana var. fraterna.The most significant activity has been found with diethyl N-(4-nitrophenyl)-N,N''-guanidinedicarboxylate.In pesticidal screening the compounds have shown fungicidal activity and particularly ovicidal activity against Tetranychus urticae which activity is increased with the compounds having a nitro group in the benzene ring.
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