Synthesis from quebrachitol of 1L-chiro-inositol 2,3,5-trisphosphate, an inhibitor of the enzymes of 1D-myo-inositol 1,4,5-trisphosphate metabolism

DOI: 10.1016/0008-6215(92)85042-X

Source and publish data:

Carbohydrate Research p. 107 - 115 (1992)

Update date:2022-07-30

Topics: Starting Material

Authors:

Liu Liu

Nahorski

Potter Potter

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Article abstract of DOI:10.1016/0008-6215(92)85042-X

L-Quebrachitol was O-demethylated to give 1L-chiro-inositol which, on treatment with dibutyltin oxide, benzyl chloride, and tetrabutylammonium iodide in acetonitrile, gave mainly crystalline 1L-2,3,5-tri-O-benzyl-chiro-inositol (5a) together with 1L-2,3,5

Full text of DOI:10.1016/0008-6215(92)85042-X

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