Organic and Biomolecular Chemistry p. 2373 - 2376 (2012)
Update date:2022-08-03
Topics:
Nguyen, Son Hong
Trotta, Adam H.
Cao, John
Straub, Timothy J.
Bennett, Clay S.
The application of the safety-catch linker concept to solid-phase glycoconjugate synthesis is described. The process allows for direct conjugation of resin bound glycans to complex aglycones during cleavage. Large excesses of either coupling partner are not required, and even very hindered alcohols serve as acceptors in the reaction. The Royal Society of Chemistry 2012.
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