Asymmetric synthesis of enantiomerically pure (-)-(1'R,4'R)-dioxolane-thymine and its anti-HIV activity

DOI: 10.1016/S0040-4039(00)79377-4

Source and publish data:

Tetrahedron Letters p. 3791 - 3794 (1991)

Update date:2022-08-03

Topics:

Authors:

Chu Chu

Ahn Ahn

Kim Kim

Beach Beach

Alves Alves

Jeong Jeong

Islam Islam

Van Roey

Schinazi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)79377-4

An asymmetric synthesis leading to the enantiomerically pure dioxolane-T has been achieved and its crystal structure has been determined and compared to the previously reported racemate. (-)-(1'R,4'R)-dioxolane-T was found to have potent and selective ant

Full text of DOI:10.1016/S0040-4039(00)79377-4

Products guided by the article

Product name:(-)-(2R,4R,1'S)-4-(2-O-benzoyl-1-hydroxyethyl)-2-<<(tert-butyldiphenylsilyl)oxy>methyl>dioxolane

Cas No:136884-12-3

R&D Labs maybe for 136884-12-3

NINGBO PANGS CHEM INT’L CO., LTD.

Contact:+86-0574-27666801

Address:Floor 21, Building 11, Xintiandi, No. 689, Shijiroad, Ningbo, Zhejiang, China
Guangxi Bonger Pharmaceutical Co., Ltd

website:http://napo.lookchem.com/

Contact:+86-18817331185

Address:Donghai Industrial Zone, Tiandong Country,Guangxi,China
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.

Contact:86-532-88250866

Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
Laizhou City Laiyu Chemical CO.,Ltd

Contact:+86-535-2719337/2719339

Address:Chenggang road zhuyou laizhou City Shangdong China

Relevant to this article

Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein

Doi:10.1016/j.ejmech.2020.112595
(2020)
Cycloaddition of nitrile oxides to 3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-α-D-ribo-hex-5-enofuranose

Doi:10.1016/0008-6215(92)84181-Q
(1991)
Dispersion energy enforced dimerization of a cyclic disilylated plumbylene

Doi:10.1021/ja300654t
(2012)
Studies on the Mechanism of Deacetoxy-Deacetylcephalosporin C Synthase using Cyclopropyl Substituted Cephalosporin Probes

Doi:10.1039/c39910000768
(1991)
Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors

Doi:10.1016/j.bmc.2013.11.045
(2014)
NEW OPTICALLY RESOLVED PERFLUORO(2-DIALKYLAMINO-PROPIONIC ACIDS)

Doi:10.1016/S0022-1139(00)80130-X
(1991)

Article Doi