
Journal of the Chemical Society. Chemical communications p. 768 - 770 (1991)
Update date:2022-08-03
Topics:
Baldwin, Jack E.
Adlington, Robert M.
Crouch, Nicholas P.
Keeping, John W.
Leppard, Simon W.
et al.
Cyclopropyl substituted cephalosporin analogues were prepared and evaluated as substrates for the FeII/α-ketoglutarate dependent oxygenase, DAOC-DAC synthase; the first example of catalytic product formation from a cyclopropyl ring cleavage pathway by an α-ketoglutarate dependent oxygenase is reported.
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