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Anticonvulsants related to U-54494 prepared from cis-1,2- and cis-2,3- diaminotetralin

DOI: 10.1016/S0040-4020(01)86548-0

Source and publish data:

Tetrahedron p. 6157 - 6162 (1991)

Update date:2022-09-26

Topics:

Authors:

D'Andrea, Stan V.D'Andrea, Stan V.

Freeman, Jeremiah P.Freeman, Jeremiah P.

Von Voigtlander, Philip F.Von Voigtlander, Philip F.

Szmuszkovicz, JacobSzmuszkovicz, Jacob

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Article abstract of DOI:10.1016/S0040-4020(01)86548-0

cis-Diaminotetralins 4 and 10 were converted in 4 steps to benzologs of the novel anticonvulsant U-54494. Attempted alkylation of 4 and 10 with 1,4-dibromobutane provided mixtures of the bis-pyrrolidino compounds and starting free bases together with the

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Full text of DOI:10.1016/S0040-4020(01)86548-0

Products guided by the article

Product name:3,4-Dichloro-N-methyl-N-((1R,2S)-2-pyrrolidin-1-yl-1,2,3,4-tetrahydro-naphthalen-1-yl)-benzamide

Cas No:136908-78-6

136908-78-6

R&D Labs maybe for 136908-78-6

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