Anticonvulsants related to U-54494 prepared from cis-1,2- and cis-2,3- diaminotetralin

DOI: 10.1016/S0040-4020(01)86548-0

Source and publish data:

Tetrahedron p. 6157 - 6162 (1991)

Update date:2022-09-26

Topics:

Authors:

D'Andrea, Stan V.

Freeman, Jeremiah P.

Von Voigtlander, Philip F.

Szmuszkovicz, Jacob

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Article abstract of DOI:10.1016/S0040-4020(01)86548-0

cis-Diaminotetralins 4 and 10 were converted in 4 steps to benzologs of the novel anticonvulsant U-54494. Attempted alkylation of 4 and 10 with 1,4-dibromobutane provided mixtures of the bis-pyrrolidino compounds and starting free bases together with the

Full text of DOI:10.1016/S0040-4020(01)86548-0

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