Synthesis, Molecular Modeling Studies, and Muscarinic Receptor Activity of Azaprophen Analogues

DOI: 10.1021/jm00115a003

Source and publish data:

Journal of Medicinal Chemistry p. 3164 - 3171 (1991)

Update date:2022-07-30

Topics:

Authors:

Triggle, David J.

Kwon, Yong Who

Abraham, Philip

Pitner, J. Bruce

Mascarella, S. Wayne

Carroll, F. I.

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Article abstract of DOI:10.1021/jm00115a003

Synthesis, radioligand binding, and pharmacologic activities of a series of muscarinic receptor ligands including and related to azaprophen (6-methyl-6-azabicyclo<3.2.1>octan-3α-ol 2,2-diphenylpropionate, 1) have been measured to determine activity and se

Full text of DOI:10.1021/jm00115a003

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Product name:2,2-Diphenyl-propionic acid (1S,3R,5R)-6-methyl-6-aza-bicyclo[3.2.1]oct-3-yl ester

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