Tetrahedron p. 7171 - 7178 (1991)
Update date:2022-07-30
Topics:
Curtis, Neil R.
Holmes, Andrew B.
Looney, Mark G.
An advanced intermediate for the synthesis of the Laurencia oxonane natural product obtusenyne 1, namely the unsaturated nine-membered lactone 3, was efficiently prepared in seven steps from (E)-3-hexenoic acid 7.The key transformation was the Claisen rearrangement of the vinyl ketene acetal 4, which represents novel methodology for the preparation of such unsaturated nine-membered lactones. Key words: medium ring; unsaturated lactone; Claisen rearrangement; vinyl ketene acetal; selenoxide elimination.
View Morewebsite:http://www.sagechem.com
Contact:+86-571-86818502
Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
Contact:+86-10-67147360/67107388
Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Ji'an Hairui Natural Plant Co. Ltd.
Contact:0796-8105528
Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province
Jinan Yijialian Economic and Trade Development Co., Ltd.
Contact:+86 0531-66729596
Address:jinan
Shandong Yaroma Perfumery Co., Ltd.
Contact:+86- 531- 88024598
Address:7-702 Caizhi Central, 59 Gong Ye South Road, Jinan City,250101, P. R. China
Doi:10.1016/j.tetlet.2014.04.126
(2014)Doi:10.1016/j.dyepig.2014.04.018
(2014)Doi:10.1016/j.tetlet.2012.03.025
(2012)Doi:10.1039/c6ob01583b
(2016)Doi:10.1002/ejoc.201101744
(2012)Doi:10.1002/ejoc.201101635
(2012)
