Rapid room-temperature 11C-methylation of arylamines with [ 11C]methyl iodide promoted by solid inorganic-bases in DMF

DOI: 10.1002/ejoc.201101499

Source and publish data:

European Journal of Organic Chemistry p. 1303 - 1310 (2012)

Update date:2022-08-05

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Authors:

Cai, Lisheng

Xu, Rong

Guo, Xuelei

Pike, Victor W.

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Article abstract of DOI:10.1002/ejoc.201101499

[¹¹C]Methyl iodide is the most widely used reagent for labeling radiotracers with carbon-11 (t_1/2 = 20.4 min) for molecular imaging with positron emission tomography. However, some substrates for labeling, especially primary arylamin

Full text of DOI:10.1002/ejoc.201101499

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