Asymmetric michael addition reactions between 3-substituted benzofuran-2(3H)-ones and 1,1-bis(phenylsulfonyl)ethylene catalyzed by bifunctional catalysts containing tertiary amine and thiourea groups

Article abstract of DOI:10.1002/ejoc.201101765

Highly enantioselective catalytic conjugate additions of 3-substituted benzofuran-2(3H)-ones to 1,1-bis(phenylsulfonyl)ethylene in the presence of catalysts based on Cinchona alkaloids and containing tertiary amine and thiourea groups have been developed.