Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

DOI: 10.1016/j.bmcl.2018.11.014

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 329 - 333 (2019)

Update date:2022-07-31

Topics:

Authors:

Yuan, Yue

Subedi, Lalita

Lim, Daesung

Jung, Jae-Kyung

Kim, Sun Yeou

Seo, Seung-Yong

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Article abstract of DOI:10.1016/j.bmcl.2018.11.014

Novel isoxazole and pyrazole analogs based on natural biphenyl-neolignan honokiol were synthesized and evaluated for their inhibitory activities against nitric oxide production in lipopolysaccharide-activated BV-2 microglial cells. The isoxazole skeleton

Full text of DOI:10.1016/j.bmcl.2018.11.014

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