Bioorganic and Medicinal Chemistry p. 4330 - 4335 (2018)
Update date:2022-09-26
Topics:
Piotrkowska, Barbara
Nerdinger, Sven
Schreiner, Erwin
Seli?, Lovro
Graczyk, Piotr P.
A modification of the Nenitzescu reaction was used to obtain Dronedarone from quinonimine 20 and 1,3-diketone 14 (R = CH2CH2CH2NBu2) in a two-stage process in almost 55% overall yield. Our results represent significant improvement over other state-of-the-art methods as no extra steps for the decoration of the benzofuran core are required.
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Doi:10.1080/14756366.2016.1220375
(2016)Doi:10.1021/jo500629d
(2014)Doi:10.1039/c2cc30995e
(2012)Doi:10.1134/S1070428012040136
(2012)Doi:10.1016/S0022-2860(96)09359-3
(1997)Doi:10.1021/ic3006794
(2012)