SYNTHESIS OF 18-SUBSTITUTED ANDROST-4-EN-3-ONE DERIVATIVES AS POTENTIAL INHIBITORS OF ALDOSTERONE BIOSYNTHESIS

DOI: 10.1016/S0040-4020(01)89733-7

Source and publish data:

Tetrahedron p. 7309 - 7322 (1991)

Update date:2022-08-06

Topics:

Authors:

Viger, Antoinette

Coustal, Suzy

Schambel, Philippe

Marquet, Andree

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)89733-7

Androst-4-en-3-one derivatives substituted at the 18-methyl group bearing a 17-keto or 17-spirolactone function have been synthesized and tested in vitro as inhibitors of aldosterone biosynthesis

Full text of DOI:10.1016/S0040-4020(01)89733-7

Products guided by the article

Product name:18-Acetoxy-17α-(4-methoxyphenoxy)-androst-4-en-3-one

Cas No:137576-81-9

R&D Labs maybe for 137576-81-9

Xinchang Yueding Chemical Co., Ltd.

Contact:86-571-56926323

Address:NO.90 BEIMENCHENGWAI CHENGGUAN TOWN XINCHANG
TIC Gums, Inc.

Contact:410-273-7300; 800-221-3953

Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Shanghai Bojing Chemical Co., Ltd.

Contact:021-37122233

Address:6F Buildiing 11,No.388,Baifu Road,District Fengxian.Shanghai, China.
Shanghai Puda Chemical Co.,Ltd

Contact:+86+571+56565965

Address:10F Haiyue Building,Danfeng Road,Binjiang District,Hangzhou,China
Shanghai Gsyn Chemical Co.,Ltd.

Contact:86-021-67158290

Address:86-021-67158291

Relevant to this article

Panchromatic donor-acceptor-acceptor sensitizers based on 4H-cyclopenta[2,1-b:3,4-b′]dithiophen-4-one as a strong acceptor for dye-sensitized solar cells

Doi:10.1016/j.dyepig.2012.03.002
(2012)
Polymeric temperature and pH fluorescent sensor synthesized by reversible addition-fragmentation chain transfer polymerization

Doi:10.1002/pola.25995
(2012)
Enantiodifferentiating Functionalization of Prochiral Diols by Highly Stereoselective Ring-Cleavage Reaction of Spiroacetals Derived from l-Menthone with Allyltrimethylsilane-Titanium-Tetrachloride

Doi:10.1246/cl.1990.1441
(1990)
Reactions of Ethoxycarbonylmethylene(triphenyl)phosphorane with some ortho-Quinones in the Presence of Triphenylphosphine, Alcohols and Acetic Anhydride

Doi:10.1039/P19920000283
(1992)
Catalytic asymmetric sulfenylation of unprotected 3-substituted oxindoles

Doi:10.1021/ol3009446
(2012)
The binary reagent PhI(OAc)₂-Mg(ClO₄)₂: a SET induced ring enlargement of furan derivatives into pyranones

Doi:10.1016/0040-4039(95)91393-K
(1995)

Article Doi