
Tetrahedron Letters p. 4687 - 4690 (1991)
Update date:2022-07-30
Topics:
Jauch, Johann
Schurig, Volker
An improved, highly diastereoselective procedure is described for the preparation of substituted 4-hydroxy-4,5-dihydrofurans 4 which are structural elements that occur in azadirachtin and several other biologically active natural products. Key Words: Acetylene-dicarboxylic-acid diesters; α-hydroxy-ketones; substituted 4-hydroxy-4,5-dihydrofurans; LiBr-activated cyclization; natural products
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