Derivatives of 8-hydroxyquinoline - Antibacterial agents that target intra- and extracellular Gram-negative pathogens

DOI: 10.1016/j.bmcl.2012.03.096

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3550 - 3553 (2012)

Update date:2022-07-30

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Authors:

Enquist, Per-Anders

Gylfe, ?sa

H?gglund, Ulrik

Lindstr?m, Pia

Norberg-Scherman, Henrik

Sundin, Charlotta

Elofsson, Mikael

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Article abstract of DOI:10.1016/j.bmcl.2012.03.096

Small molecule screening identified 5-nitro-7-((4-phenylpiperazine-1-yl-) methyl)quinolin-8-ol INP1750 as a putative inhibitor of type III secretion (T3S) in the Gram-negative pathogen Yersinia pseudotuberculosis. In this study we report structure-activit

Full text of DOI:10.1016/j.bmcl.2012.03.096

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