Journal of the American Chemical Society p. 9126 - 9129 (2012)
Update date:2022-08-03
Topics:
Zi, Weiwei
Xie, Weiqing
Ma, Dawei
An asymmetric total synthesis of the Akuammiline alkaloid (-)-vincorine (18 steps from 5-methoxytryptamine, 5% overall yield) is described. The key steps include Pd-catalyzed direct C-H functionalization of indole derivatives, organocatalyzed asymmetric M
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