Chemical and Pharmaceutical Bulletin p. 375 - 376 (1994)
Update date:2022-07-31
Topics:
Natoli
Ceraulo
Lamartina
Ferrugia
The condensation reaction under acid condition of the benzylic alcohols 1, 2 and 3 with the hexadeutero dimethoxybenzenes 4, 5 and 6 leads to the expected hexadeutero bis(dimethoxyphenyl)-2-methylpropanes 7, 8 and 9, respectively. However, the presence of both dodecadeutero and unlabelled 1- bis(2,4-dimethoxyphenyl)-2-methylpropanes 10 and 11 indicates that 9 undergoes a rapid degenerate dealkylation-alkylation reaction.
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Doi:10.1016/S0040-4039(00)93416-6
(1991)Doi:10.1016/j.bmc.2012.03.061
(2012)Doi:10.1002/anie.201200731
(2012)Doi:10.1039/c2cc31247f
(2012)Doi:10.1016/0022-328X(94)80122-3
(1994)Doi:10.1016/j.bmcl.2012.04.037
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