Synthesis of kojic acid-derived copper-chelating apoptosis inducing agents

DOI: 10.1007/s00044-012-0094-y

Source and publish data:

Medicinal Chemistry Research p. 995 - 1003 (2013)

Update date:2022-08-03

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Authors:

Chen, Yu-Hua

Lu, Pei-Jung

Hulme, Christopher

Shaw, Arthur Y.

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Article abstract of DOI:10.1007/s00044-012-0094-y

Three classes of kojic acid derivatives were synthesized and examined for their antiproliferative activity against HeLa cells. Both 8b and 11 co-treated with copper ion exhibited synergistic effect on the HeLa cell growth inhibition with GI₅₀ v

Full text of DOI:10.1007/s00044-012-0094-y

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