Selective functionalization of the C2 hydroxyl group of N-carbobenzyloxy-4,6-O-benzylidene-1-deoxynojirimycin

Article abstract of DOI:10.1016/S0040-4039(00)93531-7

1-Deoxynojirimycin was converted into its N-CBZ-4,6-O-benzylidene derivative 2 in two steps in 51% yield. Compound 2 could be regioselectively functionalized at the C2 hydroxyl group by activation with di-n-butyltin oxide, followed by reaction of the resu