Tetrahedron p. 2939 - 2946 (1995)
Update date:2022-07-30
Topics:
Schick, Hans
Ludwig, Ralf
Kleiner, Katharina
Kunath, Annamarie
Di-, tri-, and tetrasubstituted β-lactones are accessible in a one-step procedure by a Reformatsky reaction of phenyl α-bromoalkanoates with ketones or aldehydes at a sacrificial indium anode. With indium powder comparable results are obtained. The yield of β-lactones is significantly lower, if zinc is used instead of indium.
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(1970)
