Synthesis of Chiral Bitetralin-strapped "Twin Coronet" Porphyrins. Catalytic and Asymmetric Epoxidation of Styrene Derivatives

Article abstract of DOI:10.1246/cl.1991.1933

"Twin-coronet" porphyrins bearing optically active 1,1'-bitetrahydronaphthalene derivatives on the both faces of the porphyrin were prepared as enantioselective oxidation catalysts modeling on cytochrome P-450s.The eclipsed isomer of the corresponding iron(III) porphyrins catalyzed epoxidation of styrenes substituted with electron-withdrawing groups in high e.e. (61-89 percent) and high product selectivity.