On the reversal of the stereoselectivity in the Evans aldol reaction of α-amino aldehydes

DOI: 10.1016/0040-4039(91)80500-6

Source and publish data:

Tetrahedron Letters p. 7287 - 7290 (1991)

Update date:2022-08-03

Topics:

Authors:

Hayashi Hayashi

Hamada Hamada

Shioiri Shioiri

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(91)80500-6

Reversal of the stereoselectivity in the Evans aldol reaction of Boc-(S)-prolinal (3), observed during the total synthesis of dolastatin 10 (1), was proved to be due to the amounts of dibutylboron triflate and triethylamine. (R)-Alaninal derivatives (14)

Full text of DOI:10.1016/0040-4039(91)80500-6

Products guided by the article

Product name:[(1S,2R,3R)-2-Hydroxy-1-isopropyl-3-methyl-4-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-4-oxo-butyl]-methyl-carbamic acid tert-butyl ester

Cas No:138802-20-7

R&D Labs maybe for 138802-20-7

A.M FOOD CHEMICAL CO., LIMITED

Contact:86-531-87100375

Address:20Floor，Bblock，1Building，pharma-valley，Jinan，China
TIANJIN GST CHEMICAL TECHNOLOGY CO., LTD

Contact:+86-22-25210964

Address:Room. 208, No. -12-C, No. 13, Xinbei Road, Tanggu District, New Haixin Area, Tianjin City, China
Huangshan Honghui Pharm Technology Co., Ltd.(expird)

website:http://www.honghuichem.com

Contact:18855958372

Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province
WUHU HUAHAI BIOLOGY ENGINEERING CO LTD

Contact:+86-553-3836920

Address:7/F NO.82 LAODONG ROAD WUHU CHINA
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China

Relevant to this article

Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea

Doi:10.1016/j.bmcl.2012.04.133
(2012)
Reactions of bis(alkyl)yttrium complexes supported by bulky N,N ligands with 2,6-diisopropylaniline and phenylacetylene

Doi:10.1021/om300377h
(2012)
Synthesis of the Staurosporine Aglycon

Doi:10.1021/jo00033a036
(1992)
ASYMMETRIC AMPLIFICATION IN NICKEL-CATALYZED CONJUGATE ADDITION TO CHALCONE

Doi:10.1016/S0957-4166(00)86124-8
(1991)
A New Synthesis of Phthalides by Internal Trapping in Ortho-Lithiated Carbamates Derived from Benzylic Alcohols

Doi:10.1021/jo00033a024
(1992)
Synthesis of 6-Aryl-5-fluoropicolinate Herbicides via Halex Reaction of Tetrachloropicolinonitrile

Doi:10.1021/acs.oprd.9b00197
(2019)

Article Doi