AN EFFICIENT ROUTE TO C-4 LINKED IMIDAZOLE NUCLEOSIDES: SYNTHESIS OF 2-CARBAMOYL-4-(2'-DEOXY-β-D-RIBOFURANOSYL)IMIDAZOLE

Article abstract of DOI:10.1016/0040-4039(91)80199-G

The first synthesis of an imidazole C-nucleoside linked through C-4, 2-carbamoyl-4-(2'-deoxy-β-D-ribofuranosyl)imidazole was achieved by way of a nine-step sequence starting from 2-deoxy-3,5-di-O-p-toluoyl-D-erythro-pentofuranosyl chloride.