Synthesis of 5′,8-cyclopurine and of 5′,6-cyclodihydropyrimidine nucleosides using intramolecular radical cyclisation based on the aryl telluride radical exchange process

Article abstract of DOI:10.1016/S0040-4020(01)80885-1

The synthesis of C-cyclopurine and C-cyclodihydropyrimidine nucleosides has been effected using 5′-aryltelluronucleosides. Generation of methyl radicals from the photolysis of the acetyl derivative of N-hydroxy-2-thiopyridone permitted, by radical exchang