Agents for the treatment of overactive detrusor. VIII. Synthesis and pharmacological properties of 4,4-diphenyl-2-cycloalkenylamines including FK584 and 3,3- or 4,4-diphenylcycloalkylamines

DOI: 10.1248/cpb.43.71

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 71 - 77 (1995)

Update date:2022-08-03

Topics:

Authors:

Taniguchi

Okumura Okumura

Take Take

Tsubaki Tsubaki

Terai Terai

Nakanishi

Shiokawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.43.71

This article describes the synthesis of 4,4-diphenyl-2-cycloalkenylamines (3, 5a) including PK584 (S(-)-3a) and 3,3- or 4,4-diphenylcycloalkylamines (2, 4, 5b), and their inhibitory activities against detrusor contraction. The order of inhibitory activity

Full text of DOI:10.1248/cpb.43.71

NII-Electronic Library Service

Products guided by the article

Product name:Benzene, 1,1'-(4-azido-2-cyclopenten-1-ylidene)bis-

Cas No:138951-98-1

R&D Labs maybe for 138951-98-1

Molobelamltrading

Contact:27-792-602929

Address:SIDNEY MUFAMADI STREET 009949 X44 0700 POLOKWANE,LIMPOPO
Shanghai Micro-mega Industry Co., Ltd.

Contact:0086-21-34628682;57153848

Address:Rm413,No.413,West Meilong Road, Minhang District,Shanghai P R China
Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.

Contact:+86-15853188990

Address:Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China
Cartoon Ingredients Co., Ltd

website:http://www.cartoonchem.com/

Contact:+86-25-58074918

Address:Room 2109, RuiHua Business Center,315 South ZhongShan Road, Nanjing 210001, China
Nanjing Xi Ze Biological Technology Co., Ltd

Contact:86-025-66023220

Address:Address: Nanjin Qixia District Maigaoqiao R & D base in Pioneer Park Chun Yin Road 18-A928

Relevant to this article

Heterobifunctional ligands: Practical chemoenzymatic synthesis of a cell adhesive glycopeptide that interacts with both selectins and integrins

Doi:10.1021/jm000295r
(2001)
Asymmetric dihydroxylation onto the α,β-unsaturated carboxylic ester derivatives of camptothecin

Doi:10.3987/COM-97-7892
(1997)
Alkenylborane-derived frustrated Lewis pairs: Metal-free catalytic hydrogenation reactions of electron-deficient alkenes

Doi:10.1021/om3006068
(2012)
α-Amination of keto-nitrones via Multihetero-Cope rearrangement employing an imidoyl chloride reagent

Doi:10.1039/c2cc33401a
(2012)
Thermally induced [3+2] cyclization of aniline-tethered alkylidenecyclopropanes: A facile synthetic protocol of pyrrolo[1,2-a]indoles

Doi:10.1039/c2cc33269h
(2012)
An efficient synthesis of dithiocarbamates under ultrasound irradiation in water

Doi:10.1007/s00706-011-0687-z
(2012)

Article Doi