Synthesis and in vitro antibacterial activity of 2β and 2α-(substituted methyl) phenoxymethylpenicillins and an oxidation product

DOI: 10.1016/0223-5234(91)90005-8

Source and publish data:

European Journal of Medicinal Chemistry p. 791 - 797 (1991)

Update date:2022-07-29

Topics:

Authors:

Singh, MP

Reddy, AVN

Singh, R

Micetich, RG

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Article abstract of DOI:10.1016/0223-5234(91)90005-8

The effect of tereochemical changes on the antibacterial activity of a series of 2-substituted methyl-6β-phenoxyacetamido penams synthesized in our laboratory was studied.The 2α-heteroarylthiomethyl penams were found to be more active than the 2β-substitu

Full text of DOI:10.1016/0223-5234(91)90005-8

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Product name:trichloroethyl 2β-<(2-methyl-1,3,4-thiadiazol-5-yl)thiomethyl>-2α-methyl-6β-(phenoxyacetamido)-penam-3α-carboxylate

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