Regioselectivity in the 1,3-Dipolar Cycloaddition of Nitrile Oxides to 3,3-Methylene-5,5-dimethyl-2-pyrrolidinone

DOI: 10.1007/BF00815920

Source and publish data:

Monatshefte fur Chemie p. 821 - 828 (1991)

Update date:2022-07-30

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Authors:

Oravec, Peter

Fisera, Lubor

Ertl, Peter

Vegh, Daniel

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Article abstract of DOI:10.1007/BF00815920

Nitrile oxides add regioselectively to the carbon-carbon double bond of 3,3-methylene-5,5-dimethyl-2-pyrrolidinone (1), giving exclusively spiro-isoxazolines: 3-aryl-6-oxo-8,8-dimethyl-1-oxa-2,7-diazaspiro<4.4>non-2-enes 3a-l.The regiochemistry of the 1,3

Full text of DOI:10.1007/BF00815920

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