6-(4-Morpholino-phenyl)-4,5-dihydro-2H-pyridazine-3-ones: potent platelet aggregation inhibitors and antithrombotics

Article abstract of DOI:10.1016/0223-5234(91)90121-3

A series of di- and tri-substituted 6-phenyl-4,5-dihydro-2H-pyridazine-3-ones is described.The compounds were designed to be antithrombotics and were assessed for their inhibitory properties on platelet aggregation and on thrombus formation in an arteriov