Gold(I)-catalyzed cycloisomerization of nitrogen- and oxygen-tethered alkylidenecyclopropanes to tricyclic compounds

Article abstract of DOI:10.1002/chem.201200978

A new construction of tricyclic compounds has been developed from a gold-catalyzed cycloisomerization of alkylidenecyclopropanes tethered by alkynes, giving the corresponding nitrogen- and oxygen-containing six-membered heterocyclic compounds in high yields under very mild conditions (see scheme; Ts=4-toluenesulfonyl, Ns=4-nitrobenzenesulfonyl, Bs=4-bromobenzenesulfonyl).