Asymmetric Synthesis of Indoloquinolizidin-2-ones Congeners to Yohimbine-Type Alkaloids

DOI: 10.1016/S0040-4020(01)80309-4

Source and publish data:

Tetrahedron p. 397 - 416 (1993)

Update date:2022-08-04

Topics:

Authors:

Waldmann, Herbert

Braun, Matthias

Weymann, Markus

Gewehr, Markus

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Article abstract of DOI:10.1016/S0040-4020(01)80309-4

Schiff bases derived from tryptophan methyl ester and tryptamine react with Danishefkys diene in the presence of ZnCl2 to give enaminones which are subsequently transformed into indolo<2,3-a>quinolizidin-2-ones by acid-catalyzed cyclization.These tetracyc

Full text of DOI:10.1016/S0040-4020(01)80309-4

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