
Chemical and Pharmaceutical Bulletin p. 2842 - 2848 (1991)
Update date:2022-08-04
Topics:
Watanabe
Matsuura
Shirahase
Ohtani
The synthesis of 16 metabolites of S-1452, an orally active thromboxane A2 (TXA2) receptor antagonist, is described. Regioselective hydroxylation at C-5 or C-6 of the bicyclo[2.2.1]heptane skeleton of the optically active intermediat
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