Asymmetric synthesis of diethyl α-amino-α-alkyl-phosphonates by alkylation of the chiral Schiff base derived from (+)-ketopinic acid and diethylaminomethyl phosphonate

Article abstract of DOI:10.1080/00397919208021082

The alkylation of the chiral Schiff base derived from the condensation of (+)-ketopinic acid and diethyl aminomethylphosphonate followed by hydrolysis affords diethyl (S)-α-amino-α-alkyl phosphonates with high enantiomeric excesses when benzyl or allyl ha

Full text of DOI:10.1080/00397919208021082

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Synthetic Communications: An
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Organic Chemistry
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Asymmetric Synthesis of
Diethyl α-Amino-α-Alkyl-
Phosphonates by Alkylation
of the Chiral Schiff Base
Derived from (+)-Ketopinic
Acid and Diethylaminomethyl
Phosphonate
M. Ferrari a , G. Jommi a , G. Miglierini a , R.
Pagliarin a & M. Sisti a
a Dipartimento di Chimica, Organica e Industriale
Università, degli Studi di Milano Via Venezian, 21,
20133, Milano, Italy
Version of record first published: 23 Sep 2006
To cite this article: M. Ferrari, G. Jommi, G. Miglierini, R. Pagliarin & M. Sisti (1992):
Asymmetric Synthesis of Diethyl α-Amino-α-Alkyl-Phosphonates by Alkylation of
the Chiral Schiff Base Derived from (+)-Ketopinic Acid and Diethylaminomethyl
Phosphonate, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 22:1, 107-123
To link to this article: http://dx.doi.org/10.1080/00397919208021082
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