Bioreductive fluorescent markers for hypoxic cells: A study of 2- nitroimidazoles with 1-substituents containing fluorescent, bridgehead- nitrogen, bicyclic systems

DOI: 10.1021/jm00088a030

Source and publish data:

Journal of Medicinal Chemistry p. 1920 - 1926 (1992)

Update date:2022-08-05

Topics:

Authors:

Hodgkiss

Middleton

Parrick Parrick

Rami Rami

Wardman Wardman

Wilson Wilson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00088a030

The oxygen-sensitive bioreductive binding of 2-nitroimidazoles labeled with fluorescent side chains has been used to stain hypoxic mammalian cells selectively. Several novel compounds were synthesized with a 1-substituent containing a fluorescent, bicycli

Full text of DOI:10.1021/jm00088a030

Products guided by the article

Product name:1H-Imidazole-1-ethanol, a-[[[4-(2-indolizinyl)phenyl]amino]methyl]-2-nitro-

Cas No:139705-75-2

R&D Labs maybe for 139705-75-2

Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang
Sino-Japan Chemical Co., Ltd.

website:http://www.sjc.com.tw

Contact:(886) 2-2396-6223

Address:14Fl., No. 99. Sec. 2, Jen Ai Road
Hangzhou LINGEBA Technology Co., Ltd.

Contact:+0086-571-87389059

Address:Office 1-913,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China
Anhui Xinyuan Technology Co.,Ltd

Contact:0086-559-3515800

Address:No.16 Zijin Rd, Circular Economic Zone, Huizhou District, Huangshan Anhui China
SuZhou Bichal Biological Technology CO.,LTD

Contact:+86-512-68051130

Address:NO.32 huoju road HI-TECH Industrial development zone SuZhou China

Relevant to this article

Preparation and characterization of new C₂- and C ₁-symmetric nitrogen, oxygen, phosphorous, and sulfur derivatives and analogs of TADDOL. part III

Doi:10.1002/hlca.201200148
(2012)
Concise synthesis of α-(hydroxymethyl) alkyl and aryl vinyl ketones

Doi:10.1080/00397911.2011.592626
(2013)
Friction-mediated dynamic disordering of phospholipid membrane by mechanical motions of photoresponsive molecular glue: Activation of ion permeation

Doi:10.1021/ja3074424
(2012)
1,2-trans-1-Dihydroxyboryl benzyl S-glycoside as glycosyl donor

Doi:10.1016/j.carres.2014.05.010
(2014)
Aldol condensation of amides using phosphazene-based catalysis

Doi:10.1016/j.tetlet.2012.07.129
(2012)
Synthesis, characterization and X-ray structure of 3,4-lutidinyl-, 3-/4-picolyl- and pyridylselenium compounds

Doi:10.1016/j.ica.2012.03.043
(2012)

Article Doi