Visual chiral recognition of mandelic acid and α-amino acid derivatives by enantioselective gel formation and precipitation

Article abstract of DOI:10.1016/j.tetlet.2012.08.025

Novel chiral receptors based on l-phenylalanine and l-valine have been synthesized and their chiral recognition properties toward mandelic acid and N-tosyl α-amino acids are studied. The phenylalanine-based receptor undergoes enantioselective gel formation with R-mandelic acid and N-tosyl-d-valine, whereas the valine-linked receptor in their presence results in the formation of precipitates.