Chemical Communications p. 9834 - 9836 (2012)
Update date:2022-08-04
Topics:
Sutherell, Charlotte L.
Thompson, Sam
Scott, Richard T. W.
Hamilton, Andrew D.
We describe the design and synthesis of a non-peptidic β-strand mimetic composed of alternating aryl and imidazolidin-2-one rings that can be adapted to display diverse side-chains. Solid- and solution-phase data together with calculations suggest that the desired conformation for side-chain mimicry is readily accessible and well-populated. The Royal Society of Chemistry 2012.
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