BIS-ALKYLATION OF DIMETALLATED PHENYLSULFONYLMETHYL TRIFLONE. A n+1 ANNULATION STRATEGY FOR SYNTHESIS OF CYCLIC VINYL SULFONES

Article abstract of DOI:10.1016/S0040-4039(00)77705-7

Bis-metallation of phenylsulfonylmethyl triflone 4b produces a geminal dianion which can be dialkylated to afford α-phenylsulfonyl triflones.Treatment of these compounds with DBU affords vinyl sulfones which can be isomerized to allyl sulfones.