Synthesis of Enantiomerically Pure Bay-Region 10,11-Diol 8,9-Epoxide Diastereomers of the Carcinogen Dibenzacridine

DOI: 10.1021/jo00036a006

Source and publish data:

Journal of Organic Chemistry p. 2784 - 2787 (1992)

Update date:2022-07-29

Topics:

Authors:

Kumar, Subodh

Kole, Panna L.

Balani, S. K.

Jerina, Donald M.

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Article abstract of DOI:10.1021/jo00036a006

The present study describes the synthesis and configurational assignment of four enantiomerically pure, bay-region 10,11-diol 8,9-epoxide diastereomers 14-17 of dibenzacridine (1) from the corresponding optically pure trans-10,11-dihydroxy-10,11-dihy

Full text of DOI:10.1021/jo00036a006

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Product name:((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-acetic acid (10R,11R)-10-[2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-acetoxy]-8,9,10,11-tetrahydro-dibenzo[a,h]acridin-11-yl ester

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