Cyanomethyl esters: Useful protection for carboxylic acids

Article abstract of DOI:10.1080/00397919208019271

The alkylation of carboxylate salts with chloroacetonitrile yields cyanomethyl esters. Deprotection of the carboxyl group is most readily performed by stirring with an aqueous solution of sodium sulfide.

Full text of DOI:10.1080/00397919208019271

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Cyanomethyl Esters: Useful
Protection for Carboxylic Acids
Helmut M. Hugel a , K. Vijaya Bhaskai b & Robert W.
Longmore b
a Department of Applied Chemistry, Phillip Institute
of Technology, Plenty Road, Bundoora, Victoria,
3083
b Research School of Chemistry, Australian National
University, Canberra, A. C. T., 2601, Australia
Published online: 23 Sep 2006.
To cite this article: Helmut M. Hugel , K. Vijaya Bhaskai & Robert W. Longmore
(1992) Cyanomethyl Esters: Useful Protection for Carboxylic Acids, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 22:5, 693-697, DOI: 10.1080/00397919208019271
To link to this article: http://dx.doi.org/10.1080/00397919208019271
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