Synthesis and human immunodeficiency virus (HIV-1 protease inhibitory activity of tripeptide analogues containing a dioxoethylene moiety

DOI: 10.1248/cpb.42.2636

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2636 - 2640 (1994)

Update date:2022-08-04

Topics:

Authors:

Kitazaki

Asano Asano

Kato Kato

Kishimoto

Itoh Itoh

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.2636

Tripeptide analogues 2 and 3 containing a dioxoethylene moiety were designed based on the characteristic structure of the naturally occurring human immunodeficiency virus (HIV)-I protease inhibitors RPI-856 A, B, C and D (1). The compounds (2, 3) prepared showed high inhibitory activity, comparable to that of RPI-856 A, against HIV-1 protease in vitro.

Full text of DOI:10.1248/cpb.42.2636

NII-Electronic Library Service

Products guided by the article

Product name:L-Prolinamide,N2-(2-quinolinylcarbonyl)-L-asparaginyl-(aS,bS)-b-amino-a-hydroxybenzenebutanoyl-N-(1,1-dimethylethyl)-(9CI)

Cas No:141171-80-4

R&D Labs maybe for 141171-80-4

Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
Shaanxi Sinuote Biotech Co.,Ltd

Contact:+86-29-68859685

Address:No 18,Taiyuan Road ,Xi'an city ,China
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China
Simagchem Corporation

website:http://www.simagchem.com

Contact:+86-592-2680277

Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China
HangZhou HuaYe Chemical Technology Co.,Ltd

Contact:+86-13505815007

Address:hangzhou

Relevant to this article

Acylated 2,2-dimethylaziridines: Regioselectivity of ring opening by sodium thiophenolate; borderline S(N)2 due to planarization of nitrogen pyramid

Doi:10.1016/S0040-4020(01)88757-3
(1992)
Basic Character of Rare Earth Metal Alkoxides. Utilization in Catalytic C-C Bond-Forming Reactions and Catalytic Asymmetric Nitroaldol Reactions

Doi:10.1021/ja00037a068
(1992)
Peptide peak intensities enhanced by cysteine modifiers and MALDI TOF MS

Doi:10.1002/jms.3093
(2012)
Rh-catalyzed enantioselective hydrogenation of vinyl boronates for the construction of secondary boronic esters

Doi:10.1021/ol060735u
(2006)
Novel skeleton transformation reaction of α-pyrone derivatives to spirobicyclo[3.1.0]hexane derivatives using dimethylsulfoxonium methylide

Doi:10.1021/ol302942m
(2012)
Reactions of nitroxides XIII: Synthesis of the Morita-Baylis-Hillman adducts bearing a nitroxyl moiety using 4-acryloyloxy-2,2,6,6- tetramethylpiperidine-1-oxyl as a starting compound, and DABCO and quinuclidine as catalysts

Doi:10.3762/bjoc.8.171
(2012)

Article Doi