1α-Hydroxy-19-nor-vitamin D C-22 aldehyde. A valuable intermediate in the synthesis of side chain modifed 1α,25-dihydroxy-19-nor-vitamin D3

DOI: 10.1016/S0040-4039(00)79565-7

Source and publish data:

Tetrahedron Letters p. 2937 - 2940 (1992)

Update date:2022-08-05

Topics:

Authors:

Perlman, Kato L.

DeLuca, Hector F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)79565-7

A side chain homologated 1α,25-dihydroxy-19-nor-vitamin D₃ analog was prepared in a double convergent synthesis with 1α-hydroxy-19-nor-vitamin D C-22 aldehyde as a key intermediate.

Full text of DOI:10.1016/S0040-4039(00)79565-7

Products guided by the article

Product name:Acetic acid (S)-2-{(1R,3aS,7aR)-4-[2-[(3R,5R)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-propyl ester

Cas No:141404-12-8

R&D Labs maybe for 141404-12-8

Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
Suqian Ruixing Chemical Co., Ltd.

Contact:+86-527-80805666（总机）;84836008(销售)

Address:3 Jingsilu, Zone north, Hubin Xincheng Development Park, Suqian, China
Shanghai agrotree chemical co.,ltd.

Contact:+86-21-50117563

Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Evershine Chemical CO Ltd

Contact:+86-571-87010026

Address:202, Zhenhua Road,
Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County

Relevant to this article

A Micellar Catalysis Strategy for Amidation of Alkynyl Bromides: Synthesis of Ynamides in Water

Doi:10.1002/ejoc.201801601
(2019)
An oxidopyrylium cyclization/ring-opening route to polysubstituted α-hydroxytropolones

Doi:10.1021/ol302892g
(2012)
Functionalized carbodiimide mediated synthesis of 2,3-disubstituted quinazolin-4(3 H)-ones via the tandem strategy of C-nucleophilic addition and intramolecular NH-substitution cyclization

Doi:10.1055/s-0032-1316773
(2012)
Enantioselective construction of multifunctionalized spirocyclohexaneoxindoles through organocatalytic Michael-Aldol cyclization of isatin derived alkenes with linear dialdehydes

Doi:10.1039/c2ob26205c
(2012)
Palladium-Catalyzed Asymmetric Arylation of Trifluoromethylated/Perfluoroalkylated 2-Quinazolinones with High Enantioselectivity

Doi:10.1002/chem.201603105
(2016)
Benzylidene succinimides as 3C synthons for the asymmetric tandem Mannich reaction/transamidation of cyclic trifluoromethyl ketimines to obtain F₃C-containing polycyclic dihydroquinazolinones

Doi:10.1039/d0cc08131k
(2021)

Article Doi