Potential prodrug derivatives of 2',3'-didehydro-2',3'-dideoxynucleosides. Preparations and antiviral activities

DOI: 10.1021/jm00093a003

Source and publish data:

Journal of Medicinal Chemistry p. 2728 - 2735 (1992)

Update date:2022-08-05

Topics:

Authors:

Mullah Mullah

Rao Rao

Balzarini

De Clercq

Bentrude

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Article abstract of DOI:10.1021/jm00093a003

The preparations and antiviral activities of a series (4-17) of potential prodrug forms of the antivirals 2',3'-didehydro-2',3'-dideoxyadenosine (D4A) and 2',3'-didehydro-2',3'-dideoxycytosine (D4C) are reported. The 5'-phenyl and 5'-methylphosphonates (4

Full text of DOI:10.1021/jm00093a003

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