Ring expansion of benzocyclic ketones via transient alkoxyl radicals: The side chain incorporation approach

Article abstract of DOI:10.1016/S0040-4020(01)88482-9

Radical cyclisation onto carbonyl groups followed by β-sission of the resulting alkoxy radicals provides a method for the one-carbon ring expansion of benzocyclic ketones. The radicals are generated by Bu₃SnH reduction of bromomethyl moieties α