Tetrahedron Letters p. 6007 - 6010 (1992)
Update date:2022-08-02
Topics:
Kaptein, Bernard
Boesten, Wilhelmus H. J.
Broxterman, Quirinus B.
Schoemaker, Hans E.
Kamphuis, Johan
α,α-Disubstituted α-amino acid amides were prepared in 17-88 percent chemical yield by the phase-transfer catalyzed alkylation of N-benzylidene α-H amino acid amides, followed by weak acidic hydrolysis of the Schiff bases.
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Doi:10.1016/0022-1902(65)80423-7
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