Quantitative Structure-Activity Relationships of N2-Phenylguanines as Inhibitors of Herpes Simplex Virus Thymidine Kinases

DOI: 10.1021/jm00094a007

Source and publish data:

Journal of Medicinal Chemistry p. 2979 - 2983 (1992)

Update date:2022-08-05

Topics:

Authors:

Gambino, Joseph

Focher, Federico

Hildebrand, Catherine

Maga, Giovanni

Noonan, Timothy

et al. et al.

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Article abstract of DOI:10.1021/jm00094a007

Quantitative structure-activity relationships of the Hansch-type were developed to account for inhibition of thymidine kinases from Herpes simplex virus types 1 and 2 (HSV1,2) by N²-phenylguanines.Derivatives with meta and/or para substituents

Full text of DOI:10.1021/jm00094a007

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